Department of Pharmaceutical Technology and BiopharmaceuticsTeaching Staff:
History Data: The department was created in 1939 on the basis of the Institute of Training and Retraining of pharmacists with an active participation of the Corresponding Member of the Academy of Sciences of the USSR, Doctors of Pharmaceutical Sciences, Professor Ya. P. Fialkov. The Great Patriotic war suspended the activity of the Institute and the Department, but immediately after the liberation from fascist aggressors in 1944, the work was restored. There were two technological departments at that time - the Department of Drug Technology, which was headed by the Assistant Professor E.S. Skvyrska, and the Department of Technology of galena preparations, which was headed by Assistant Professor G.A. Vaisman. In the beginning of 1953, the Kyiv Institute of Advanced Education of pharmacists was reorganized into the Pharmaceutical Department of the Kyiv Institute of Advanced Education of doctors, and after the integration of technological departments, the Department of Technology of medical preparations and galena preparations was created under the supervision of Doctor of Pharmaceutical Sciences, Professor H.А. Vaisman. At that time, the research educational subjects on development and improvement of existing methods of manufacturing of medications and development of techniques of their quality control were carried out. Based on the results of the work carried out, monographs of Professor H.A. Vaisman “Questions of improvement of medicines quality” and of Professor H.A. Vaisman and N.I. Prokopovych “Incompatible combinations of components in medicinal forms” were published. Research on the use of cationites for the quantitative analysis, which had been carried out by professor H.A. Vaisman and the employees of the department for the first time in the USSR, was included into the State pharmacopoeia, 1Х edition. Year after year methods of teaching were being improved, as well as the forms of educational process and methods of training, according to the requirements of time. For more than 20 years (from 1973 to 1994), the department was headed by the Doctor of Pharmaceutical Sciences, Professor E.E. Borzunov. A high professional level and the many-sided scientific activity of the department’s teaching staff allowed carrying out the training and education of experts from all republics of the USSR and foreign countries. At that time, close connections with pharmaceutical establishments and the enterprises developed, the inventory grew stronger, and active forms and methods of work were introduced, which helps in organization of the high quality postgraduate training of pharmacists and preparation of the scientific and pedagogical staff. Professor E.E. Borzunov headed the direction of research work on theoretic-experimental substantiation of technology of peleet medical products. 40 production regulations were introduced into practice of pharmaceutical factories for manufacture of medical products. Since 1994 till 2009, the Department had been headed by the Doctor of Pharmaceutical Sciences, Professor R.S. Korytniuk. Continuing the achievements, made by Professor H.A. Vaisman and Professor E.E. Borzunov, the department’s collective provides carrying out the research work on the highest level. Professor R.S. Korytniuk established the first scientific school in Ukraine, which deals with the problem of creation of multicomponent infusion solutions. She is an author of more than 250 scientific works, including 12 patents, 3 monographs, 22 methodical recommendations. Under the supervision of Professor R.S. Korytniuk, 2 Doctor¢s theses, 10 Candidate’s theses were defended and now the preparation of doctoral, candidate and master’s works is being carried out. She takes part in a creation of the State Pharmacopoeia of Ukraine, and also in a creation of normative documents of the state level. National pharmaceutical industry produces 5 medicinal preparations, which was created by R.S. Korytniuk and under her supervision. In 2009 the department has been headed by Professor L.L. Davtian. Under her management, the improvement of quality and efficiency of teaching is carried out, new programs of courses for the improvement of pharmaceutical and medical experts are created, methodical work is improved. Professor L.L. Davtian has lead the research on theoretical and experimental substantiation of the technology of drugs with different dispersion medium. She works in the field of aerosol products, solid and mild (non solid) drugs, including drugs on dental medical films. Under the guidance of Professor L.L. Davtian two master's theses was carried out and currently she is involved in the preparing and defense of Candidate and master's works. Professor L.L. Davtian. is an author of 210 scientific works, 10 patents, 2 monographs, 2 textbooks and 8 methodical recommendations. Assistant Professor T.V. Torhova develops a direction of scientific researches of the department on technology of multicomponent infusion solutions with power substrata. She is an author more than 120 scientific works, 2 methodical recommendations, 2 copyright certificates and 12 innovations, including 4 branch innovations. Candidate of Pharmaceutical Sciences. Assistant Professor of the department I.A. Vlasenko works on a creation of mild medications, she is an author more than 60 scientific works and 5 patents. The Candidate of Pharmaceutical Sciences, Assistant Professor V.V. Rudenko is an author of 40 scientific works; he is the developer of a medicinal form new to Ukraine - peroral powders for treatment of dehydration conditions. The Candidate of Pharmaceutical Sciences, senior lecture A.O. Drozdova works of various medicinal forms. She is an author more than 20 scientific works and 2 patents. Assistants: T.F. Olifirova works on a mild dosage forms and on different antimicrobial activity. She is an author of 8 scientific works and 2 patents. Teaching and Methodological Work: The following courses are conducted at the department: For pharmaceutical – Pre-certification training: in General Pharmacy, duration 1 month. Topical Advanced Training on: a) Current issues of pharmacodynamics and pharmacokinetics of pharmacologically active substances in medications” (for pharmacists and doctors) with different duration: 4 weeks, 2 weeks and 1 week. b) Biopharmaceutical aspects of medicines and pharmacare”, duration – 1 month, c) Interactions and side effects of drugs "(for pharmacists, physicians, internists, family physicians) lasting 1 week. d) Biomedical and pharmaceutical aspects of modern drugs (for physicians, pharmacists and pharmaceutical companies), duration of 1 week and 2 weeks. e) Biopharmaceuticals and information technology in Pharmacy "(for medical representatives and personnel with secondary medical pharmaceutical education, who works in medical offices), duration of 1 week and 2 weeks. f) Medicines technology for manufacturing pharmacies”, duration - 1 week, groups are formed according to applications received. g) Traineeship Courses in General Pharmacy, duration 1 month. For pharmacists – Topical Advanced Training on: a) Pharmaceutical and medicobiological aspects in pharmaceutical work, duration 1 month and holds 5 times per year. b) Update issues of pharmacy” duration 1, 3 and 4 weeks. Internship: in General pharmacy. The faculty has an audience for 30 places, two educational rooms and three laboratories. For the improvement of quality and efficiency of teaching, new programs of courses on the improvement of pharmaceutical and medical experts and that of the teaching staff are created, methodological work, which includes methodical maintenance of educational process by means of creation of new methodical developments of lectures, practical and seminar studies, formation of tests data; by the enlargement of methods of the entering, current, intermediate and final control, and by the development of situational tasks and so on. Scientific Research Activities: Mastership, Postgraduate study and Doctoral studies are conducted at the department The basic direction of scientific researches of the department is the research and practical studies of structure and development of technologies of drugs with different dispersion medium Professor L.L. Davtian carries out research with the purpose of creation and development of the scientifically reasoned technology of the new medicinal form - stomatological periodontal membranes for the treatment of inflammatory diseases of oral cavity. This developed medication belongs to the third generation of medicines delivery system, where the interaction of components on intermolecular level is used. Assistant Professor L.L. Davtian, for the first time, proposed a new way of introduction of active substances in soft tissues of parodentium, which provides high therapeutic efficiency in treatment of inflammatory diseases of periodontal. Technological, biopharmaceutical and pharmacological researches made it possible to generalize theoretically and to experimentally confirm the fact that the therapeutic efficiency of a stomatological medications depends on the nature and quantities of auxiliary substances and under her leadership, conducted research to develop drugs with nanoparticles. Professor R.S. Korytniuk gave theoretical and experimental substantiation of technological processes that provide stability of a number of samples of plasma substitutional solutions of polyelectrolyte structure with power substrata in large-scale glass and polyvinyl chloride package, and also as dry and liquid concentrates in ampoules. It allowed, on the basis of studying the needs of resuscitation, burns and surgical clinics, to create preparations, and to scientifically reason the technology of plasma substitutional solutions with the purpose of their industrial and chemist's manufacture. Combination of technological and physical-chemical researches provided the creation of technological bases and the organization of manufacture of poly-ionic solutions of different modifications. The results of theoretical and experimental research are published in the monograph “Technology and quality control of solutions for injections in drugstores”.- Кyiv, "Zdorovya”, 1990, which is the manual for scientific-practical workers of pharmacy. Under the guidance of Professor R.S. Korytniuk, an industrial and chemical technology of combined power-poly-ionic colloid solution manufacturing for infusions and of a solution for peritoneal dialysis was developed. The techniques of the control were worked out, the projects of technological regulations and the ANDES on solutions were developed, and it helped to introduce separate fragments of technological and analytical research into industrial production. The research in the field of technology of medicines in historical aspect was as well conducted. The historical literature investigated enriched experts with knowledge on technology of medicines, and also has given a new life to some medications. Assistant Professor T.V. Torhova proposed a scientifically reasoned technology and techniques of quality control of 8 infusion poly-electrolyte solutions with glucose and sorbite for the needs of intensive and post-intensive therapy, and also a technology of a solution for organ conservation, which allows making transplantation of a pancreas on the modern level. She has also developed a technology of four samples of infusion solutions on the basis of hydroxyethyl starch, which will find its application in practice of urgent therapy. Assistant Professor T.V. Torhova was the first in Ukrainian pharmaceutical practice to carry out researches in the area of osmometry of infusion solutions, she has determined their ionograms with the purpose of a scientific substantiation of methods and principles of intensive therapy. Developing the direction of scientific research in the field of technology of medicines, Assistant Professor T.V. Torhova works on the problems of theoretical base of modeling and scientifically reasoned technology of poly-electrolyte and colloid multi-component infusion solutions with power substrata and mono-mol concentrates. The Candidate of Pharmaceutical Sciences, Assistant Professor V.V. Rudenko developed a scientifically proved technology of extemporal and industrial production, studied the stability of poly-ionic enteral medications and defined the terms of their storage. Techniques of the qualitative and quantitative analysis for the control of technological process are fulfilled, certified norms of medical means are established and the analytical normative documentation is developed. Candidate of Pharmaceutical Sciences. Assistant Professor of the department, Vlasenko I.A. developed a science-based technology and manufacturing extemporaneous dentistry soft medicinal forms. The Candidate of Pharmaceutical Sciences, senior lecture A.O. Drozdova works to create of various medicinal forms. Address: 01112, Kyiv |